Best Herbal Extracts

Botanical Ingredient


Rutaecarpine is extracted from Evodia or synthesized. Stanford Chemicals has been providing quality Rutaecarpine and many other natural plant extracts for over 25 years.

SKU HE3126 Category

Rutaecarpine Safety Tips

Handling of Rutaecarpine should only be performed by personnel trained and familiar with the handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.


  • 1. Variations in the composition of Fructus Evodiae after processing with Radix Glycyrrhizae extract.
    Xiao BY, Mao SJ, Li XD.Chin J Integr Med. 2012 Oct;18(10):782-7. doi: 10.1007/s11655-012-1178-8. Epub 2012 Sep 11.
  • 2. Stimulation of Calcitonin Gene-Related Peptide Release Through Targeting Capsaicin Receptor: A Potential Strategy for Gastric Mucosal Protection.
    Luo XJ, Liu B, Dai Z, Yang ZC, Peng J.Dig Dis Sci. 2012 Aug 24. [Epub ahead of print]
  • 3. In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion.
    Zhang YT, Huang ZB, Zhang SJ, Zhao JH, Wang Z, Liu Y, Feng NP.Int J Nanomedicine. 2012;7:2465-72. doi: 10.2147/IJN.S30616. Epub 2012 May 18.
  • 4. New topoisomerases inhibitors: synthesis of rutaecarpine derivatives and their inhibitory activity against topoisomerases.
    Kim SI, Lee SH, Lee ES, Lee CS, Jahng Y.Arch Pharm Res. 2012 May;35(5):785-9. doi: 10.1007/s12272-012-0504-1. Epub 2012 May 29.
  • 5. New glycosidic alkaloid from the nearly ripe fruits of Euodia rutaecarpa.
    Hu CQ, Li KK, Yang XW.J Asian Nat Prod Res. 2012;14(7):634-9. doi: 10.1080/10286020.2012.682154. Epub 2012 May 15.
  • 6. Transdermal behaviors comparisons among Evodia rutaecarpa extracts with different purity of evodiamine and rutaecarpine and the effect of topical formulation in vivo.
    Chen F, Li S, Li D, Ding JS.Fitoterapia. 2012 Jul;83(5):954-60. doi: 10.1016/j.fitote.2012.04.021. Epub 2012 Apr 29.
  • 7. Mosquito larvicidal activity of alkaloids and limonoids derived from Evodia rutaecarpa unripe fruits against Aedes albopictus (Diptera: Culicidae).
    Liu ZL, Liu QZ, Du SS, Deng ZW.Parasitol Res. 2012 Sep;111(3):991-6. doi: 10.1007/s00436-012-2923-9. Epub 2012 Apr 25.
  • 8. [Comparative study on pharmacokinetics of six major alkaloids in Zuojin Wan microemulsion based gel and hydrogel].
    Cheng L, Wang Y, Liu S, Wang L, Yi H, Du M, Yang H, Liang R, Yin X.Zhongguo Zhong Yao Za Zhi. 2011 Dec;36(23):3327-31. Chinese.
  • 9. [Effect of different compatibility of Wuji Wan on bile excretion of representative ingredient].
    Wang Y, Zhang Y, Li Y, Yang W, Wang Y, Chen Y, Yang Q, Li T, Dong Y, Zhu X.Zhongguo Zhong Yao Za Zhi. 2011 Dec;36(23):3319-26. Chinese.
  • 10. 2-(2-indolyl-)-4(3H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling.
    Li Z, Wang B, Hou JQ, Huang SL, Ou TM, Tan JH, An LK, Li D, Gu LQ, Huang ZS.J Enzyme Inhib Med Chem. 2012 Mar 1. [Epub ahead of print]
  • 11. Simultaneous determination and pharmacokinetic analysis of seven alkaloids and two flavonoids from rat plasma by HPLC-DAD after oral administration of Wuzhuyu decoction.
    Hu CQ, Li F, Yang XW.J Asian Nat Prod Res. 2012;14(4):370-81. doi: 10.1080/10286020.2012.656093.
  • 12. [Studies on pharmacokinetics of evodiamine and rutaecarpine in rats plasma after oral administration extracts of euodiae fructus].
    Bao T, Li Y, Weng X, Yang Q, Zhang Y, Dong Y, Zhu X.Zhongguo Zhong Yao Za Zhi. 2011 Dec;36(24):3519-22. Chinese.
  • 13. Efficient syntheses of 2,3-disubstituted natural quinazolinones via iridium catalysis.
    Fang J, Zhou J.Org Biomol Chem. 2012 Mar 28;10(12):2389-91. doi: 10.1039/c2ob07178a. Epub 2012 Feb 15.
  • 14. [Synthesis, physicochemical and pharmacological properties of pentacyclic alkaloid-analogues].
    Bubenyák M.Acta Pharm Hung. 2011;81(4):139-49. Hungarian.
  • 15. Simultaneous determination of evodiamine and rutecarpine in rabbit plasma by LC-ESI-MS and its application to pharmacokinetics.
    Lin C, Pan X, Li W, Ma J, Pan J, Cai J, Wang X, Lin G.Pharmazie. 2011 Dec;66(12):920-3.
  • 16. Pharmacokinetic comparisons of rutaecarpine and evodiamine after oral administration of Wu-Chu-Yu extracts with different purities to rats.
    Xu S, Peng J, Li Y, He L, Chen F, Zhang J, Ding J.J Ethnopharmacol. 2012 Jan 31;139(2):395-400. doi: 10.1016/j.jep.2011.11.023. Epub 2011 Nov 22.
  • 17. Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion.
    Zhang YT, Zhao JH, Zhang SJ, Zhong YZ, Wang Z, Liu Y, Shi F, Feng NP.Int J Nanomedicine. 2011;6:2469-82. doi: 10.2147/IJN.S25258. Epub 2011 Oct 21.
  • 18. Indoloquinazoline alkaloids from Euodia rutaecarpa and their cytotoxic activities.
    Huang X, Zhang YB, Yang XW.J Asian Nat Prod Res. 2011 Oct;13(11):977-83. doi: 10.1080/10286020.2011.602015. Epub 2011 Oct 10.
  • 19. Multicomponent assembly strategies for the synthesis of diverse tetrahydroisoquinoline scaffolds.
    Granger BA, Kaneda K, Martin SF.Org Lett. 2011 Sep 2;13(17):4542-5. doi: 10.1021/ol201739u. Epub 2011 Aug 11.
  • 20. Evodia rutaecarpa and Three Major Alkaloids Abrogate Influenza A Virus (H1N1)-Induced Chemokines Production and Cell Migration.
    Chiou WF, Ko HC, Wei BL.Evid Based Complement Alternat Med. 2011;2011:750513. doi: 10.1093/ecam/nep238. Epub 2011 Jun 8.


Product Name




Molecular Formula


Molecular Weight


Botanical Source

Evodia or synthesized


90%, 95% HPLC


Light yellow


25 kg/drum


Stored in cool & dry places, protected from direct sunlight and heat.

Shelf Life

2 years


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