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Licochalcone A

Licochalcone A is a chalconoid compound extracted from the root of Glycyrrhiza inflata (Chinese licorice), known for its potent anti-inflammatory, antimicrobial, and antioxidant properties. With the CAS number 58749-22-7 and a purity of ≥98% HPLC, Licochalcone A has attracted significant interest for its potential therapeutic applications in treating skin conditions, such as acne and eczema, and for its role in cancer research.

SKU HE4812 Category

Product Details

  • Product Name: Licochalcone A
  • CAS Number: 58749-22-7
  • Purity: ≥98% HPLC
  • Molecular Formula: C21H22O4
  • Molecular Weight: 338.40 g/mol
  • Appearance: Yellow crystalline powder
  • Solubility: Soluble in DMSO and ethanol, slightly soluble in water
  • Storage: Store at -20°C, protected from light and moisture

Features & Benefits

  • Anti-inflammatory Activity: Exhibits significant anti-inflammatory effects, beneficial for reducing redness and swelling in skin conditions.
  • Antimicrobial Properties: Demonstrates activity against a range of bacteria and fungi, particularly those implicated in acne.
  • Antioxidant Efficacy: Protects against oxidative stress, supporting cellular health and preventing damage.
  • Research Interest: A subject of ongoing scientific research for its potential anticancer properties and applications in skin health.


  • Pharmaceutical Research: Investigated for its potential in developing treatments for inflammatory diseases, skin conditions, and cancer.
  • Cosmetics and Skincare: Utilized in skincare products for its anti-inflammatory and antimicrobial properties, ideal for acne-prone and sensitive skin.
  • Nutraceuticals: Incorporated into dietary supplements for its antioxidant benefits and overall health support.
  • Biomedical Research: Explored in scientific studies focusing on its mechanism of action and therapeutic potential.

Safety & Compliance

  • Manufactured under strict quality control standards to ensure high purity and safety.
  • Accompanied by a comprehensive Certificate of Analysis (CoA) for quality assurance.
  • Recommended for use by healthcare professionals and researchers familiar with the handling and safety protocols of bioactive compounds.


  • Available in 20mg and 1g quantities to support a wide range of research, development, and commercial applications.
  • Packaged in air-tight containers to ensure stability and product integrity during storage and handling.









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