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Irinotecan is a topoisomerase I inhibitor used primarily in the treatment of metastatic colorectal cancer, among other cancer types. With the CAS number 97682-44-5 and a purity of ≥98% HPLC, Irinotecan is a key chemotherapeutic agent that works by inhibiting the topoisomerase I enzyme, essential for DNA replication and cell division in cancer cells. This mechanism leads to DNA damage in the cancer cells and induces cell death, thereby reducing tumor growth and spread.

SKU HE4744 Category Tag

Product Details:

  • Product Name: Irinotecan
  • CAS Number: 97682-44-5
  • Purity: ≥98% HPLC
  • Molecular Formula: C33H38N4O6
  • Molecular Weight: 586.68 g/mol
  • Appearance: White to off-white crystalline powder
  • Solubility: Soluble in DMSO, ethanol, and slightly soluble in water
  • Storage: Store at -20°C, protected from light and moisture

Features & Benefits:

  • Effective Chemotherapy Agent: Demonstrates significant efficacy in the treatment of metastatic colorectal cancer and is explored for other cancers.
  • Mechanism of Action: Inhibits topoisomerase I enzyme, preventing DNA replication in cancer cells and inducing apoptosis.
  • Clinical Use: Approved for clinical use in various formulations, including intravenous administration, as part of combination chemotherapy regimens.
  • Research Interest: Continues to be a subject of extensive research for its therapeutic potential in cancer treatment and its pharmacokinetic properties.


  • Cancer Treatment: Used as a part of combination chemotherapy regimens for the treatment of metastatic colorectal cancer and other malignancies.
  • Pharmaceutical Research: Investigated for potential use in new therapeutic strategies and formulations for cancer treatment.
  • Clinical Studies: A focus of ongoing clinical trials to explore its efficacy, safety, and potential in treating various types of cancer.

Safety & Compliance:

  • Handled with care due to its potency and potential side effects.
  • Manufactured under stringent quality control standards to ensure high purity and safety.
  • Accompanied by a comprehensive Certificate of Analysis (CoA) for quality assurance.
  • Use and handling of this chemotherapeutic agent should be performed by healthcare professionals and researchers familiar with safety protocols in oncology.


  • Available in 20mg and 1g quantities to support clinical research and development projects.
  • Packaged in air-tight containers to maintain stability and ensure product integrity during storage and handling.









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