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Demethylzeylasteral is a triterpenoid from Tripterygium wilfordii with immunosuppressive, anti-inflammatory, and anticancer properties, studied for treating autoimmune diseases, inflammation, and cancer.

SKU HE5283 Category

Demethylzeylasteral Overview

The immunomodulatory and anti-inflammatory effects of demethylzeylasteral are believed to stem from its ability to inhibit certain cell signaling pathways involved in immune response and inflammation, such as the NF-κB pathway. This compound has been studied for its potential to reduce the symptoms of rheumatoid arthritis, suppress the immune system in organ transplantation, and treat various inflammatory conditions.

Demethylzeylasteral Key Features

– Natural Source: Isolated from Tripterygium wilfordii Hook F.

– Bioactivities: Exhibits immunosuppressive and anti-inflammatory effects.

– Mechanism of Action: Acts by modulating immune cell signaling pathways and inhibiting pro-inflammatory cytokine production.

Demethylzeylasteral Applications

– Autoimmune Diseases: Potential therapeutic agent for treating conditions like rheumatoid arthritis and lupus due to its immunosuppressive properties.

– Inflammatory Disorders: Investigated for its ability to reduce inflammation in various diseases, improving symptoms and quality of life.

– Research Tool: Used in pharmacological studies to explore mechanisms of immune regulation and the development of new immunomodulatory drugs.



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