Demethylzeylasteral
Demethylzeylasteral Overview
The immunomodulatory and anti-inflammatory effects of demethylzeylasteral are believed to stem from its ability to inhibit certain cell signaling pathways involved in immune response and inflammation, such as the NF-κB pathway. This compound has been studied for its potential to reduce the symptoms of rheumatoid arthritis, suppress the immune system in organ transplantation, and treat various inflammatory conditions.
Demethylzeylasteral Key Features
– Natural Source: Isolated from Tripterygium wilfordii Hook F.
– Bioactivities: Exhibits immunosuppressive and anti-inflammatory effects.
– Mechanism of Action: Acts by modulating immune cell signaling pathways and inhibiting pro-inflammatory cytokine production.
Demethylzeylasteral Applications
– Autoimmune Diseases: Potential therapeutic agent for treating conditions like rheumatoid arthritis and lupus due to its immunosuppressive properties.
– Inflammatory Disorders: Investigated for its ability to reduce inflammation in various diseases, improving symptoms and quality of life.
– Research Tool: Used in pharmacological studies to explore mechanisms of immune regulation and the development of new immunomodulatory drugs.
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