Best Herbal Extracts

Reference Substances

Cucurbitacin E

Cucurbitacin E, also known as alpha-elaterin, is a bioactive compound from the Cucurbitaceae family, noted for its anticancer, anti-inflammatory, and antiangiogenic properties, and studied for its potential in therapeutic applications, particularly in oncology and chronic inflammation management.

SKU HE5246 Category


The traditional use of plants containing cucurbitacin E in folk medicine has prompted research into their pharmacological properties, exploring the potential for developing new therapeutic agents based on this compound. Its potent anticancer activity, coupled with anti-inflammatory and antiangiogenic properties, positions cucurbitacin E as a candidate for cancer therapy and other conditions where inflammation plays a critical role.

Cucurbitacin E Key Features

– Natural Source: Found in plants of the Cucurbitaceae family and other botanical sources known for their medicinal properties.

– Bioactivities: Exhibits potent anticancer, anti-inflammatory, and antiangiogenic activities.

– Mechanism of Action: Interferes with cellular signaling pathways, notably the JAK/STAT pathway, inhibiting cancer cell proliferation and inducing apoptosis.

Cucurbitacin E Applications

– Cancer Research: Investigated for its ability to target and inhibit the growth of various types of cancer cells, making it a subject of interest in oncology.

– Inflammatory Diseases: Its anti-inflammatory effects are explored for the treatment of chronic inflammatory conditions, offering potential therapeutic benefits.

– Antiangiogenic Therapy: The compound’s ability to inhibit angiogenesis, the process of new blood vessel formation, is relevant in cancer treatment, as it can starve tumors of nutrients and oxygen.

Cucurbitacin E Functions

– Tumor Growth Inhibition: Cucurbitacin E can inhibit the proliferation of cancer cells and promote their apoptosis, contributing to its anticancer effects.

– Suppression of Inflammation: Modulates the inflammatory response by inhibiting the production of pro-inflammatory cytokines and mediators.

– Inhibition of Angiogenesis: Prevents the formation of new blood vessels in tumors, limiting their growth and metastasis.



    There are no reviews yet.

    Be the first to review “Cucurbitacin E”

    Your email address will not be published. Required fields are marked *