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Pomegranate Husk Extract


35% 40% Punicalagin Alpha+Beta HPLC

Botanical Source:

Pericarpium Granati


25 kg/drum


Stored in cool & dry places, protected from direct sunlight and heat.

SKU HE3613 Category


Anti-cancer and anti-oxidation effects. Prevention and treatment of colon cancer, esophageal cancer, liver cancer, lung cancer, tongue, and skin cancer, and other illnesses. Enhance immune function, lower blood pressure, and sedative effect.


Pomegranate Husk Extract Safety Tips

Handling of Pomegranate Husk Extract should only be performed by personnel trained and familiar with handling potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.


  • 1. Polypodium leucotomos Extract is used to prevent and reduce the risk of infectious diseases in high performance athletes.
    Solivellas BM, Martín TC.Infect Drug Resist. 2012;5:149-53. doi: 10.2147/IDR.S29113. Epub 2012 Oct 16.
  • 2. Benefits of oral Polypodium Leucotomos extract in MM high-risk patients.
    Aguilera P, Carrera C, Puig-Butille JA, Badenas C, Lecha M, González S, Malvehy J, Puig S.J Eur Acad Dermatol Venereol. 2012 Jul 31. doi: 10.1111/j.1468-3083.2012.04659.x. [Epub ahead of print]
  • 3. Polypodium leucotomos decreases UV-induced epidermal cell proliferation and enhances p53 expression and plasma antioxidant capacity in hairless mice.
    Rodríguez-Yanes E, Juarranz Á, Cuevas J, Gonzalez S, Mallol J.Exp Dermatol. 2012 Aug;21(8):638-40. doi: 10.1111/j.1600-0625.2012.01544.x.
  • 4. Polypodium leucotomos extract in atopic dermatitis: a randomized, double-blind, placebo-controlled, multicenter trial.
    Ramírez-Bosca A, Zapater P, Betlloch I, Albero F, Martínez A, Díaz-Alperi J, Horga JF; Grupo de Anapsos en Dermatitis Atópica y centros de realización del estudio.Actas Dermosifiliogr. 2012 Sep;103(7):599-607. Epub 2012 May 3. English, Spanish.
  • 5. Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers.
    Gonzalez S, Gilaberte Y, Philips N, Juarranz A.Int J Mol Sci. 2011;12(12):8466-75. doi: 10.3390/ijms12128466. Epub 2011 Nov 29.
  • 6. Oral administration of a hydrophilic extract of Polypodium leucotomos for the prevention of polymorphic light eruption.
    Tanew A, Radakovic S, Gonzalez S, Venturini M, Calzavara-Pinton P.J Am Acad Dermatol. 2012 Jan;66(1):58-62. doi: 10.1016/j.jaad.2010.09.773. Epub 2011 Jun 22.
  • 7. Oral polypodium leucotomos extract photoprotective activity in 57 patients with idiopathic photodermatoses.
    Caccialanza M, Recalcati S, Piccinno R.G Ital Dermatol Venereol. 2011 Apr;146(2):85-7.
  • 8. Mechanistic insights in the use of a Polypodium leucotomos extract as an oral and topical photoprotective agent.
    Gonzalez S, Gilaberte Y, Philips N.Photochem Photobiol Sci. 2010 Apr;9(4):559-63. doi: 10.1039/b9pp00156e. Review.
  • 9. Decrease of ultraviolet A light-induced “common deletion” in healthy volunteers after oral Polypodium leucotomos extract supplement in a randomized clinical trial.
    Villa A, Viera MH, Amini S, Huo R, Perez O, Ruiz P, Amador A, Elgart G, Berman B.J Am Acad Dermatol. 2010 Mar;62(3):511-3. doi: 10.1016/j.jaad.2009.05.045. No abstract available.
  • 10. Polypodium leucotomos extract decreases UV-induced Cox-2 expression and inflammation, enhances DNA repair, and decreases mutagenesis in hairless mice.
    Zattra E, Coleman C, Arad S, Helms E, Levine D, Bord E, Guillaume A, El-Hajahmad M, Zwart E, van Steeg H, Gonzalez S, Kishore R, Goukassian DA.Am J Pathol. 2009 Nov;175(5):1952-61. doi: 10.2353/ajpath.2009.090351. Epub 2009 Oct 1.
  • 11. Cancer cell growth and extracellular matrix remodeling mechanism of ascorbate; beneficial modulation by P. leucotomos.
    Philips N, Dulaj L, Upadhya T.Anticancer Res. 2009 Aug;29(8):3233-8.
  • 12. Beneficial regulation of matrixmetalloproteinases and their inhibitors, fibrillar collagens and transforming growth factor-beta by Polypodium leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells.
    Philips N, Conte J, Chen YJ, Natrajan P, Taw M, Keller T, Givant J, Tuason M, Dulaj L, Leonardi D, Gonzalez S.Arch Dermatol Res. 2009 Aug;301(7):487-95. doi: 10.1007/s00403-009-0950-x. Epub 2009 Apr 17.
  • 13. Polypodium leucotomos inhibits ultraviolet B radiation-induced immunosuppression.
    Siscovick JR, Zapolanski T, Magro C, Carrington K, Prograis S, Nussbaum M, Gonzalez S, Ding W, Granstein RD.Photodermatol Photoimmunol Photomed. 2008 Jun;24(3):134-41. doi: 10.1111/j.1600-0781.2008.00352.x.
  • 14. A review of DNA repair and possible DNA-repair adjuvants and selected natural anti-oxidants.
    Emanuel P, Scheinfeld N.Dermatol Online J. 2007 Jul 13;13(3):10. Review.
  • 15. Polypodium leucotomos extract inhibits glutathione oxidation and prevents Langerhans cell depletion induced by UVB/UVA radiation in a hairless rat model.
    Mulero M, Rodríguez-Yanes E, Nogués MR, Giralt M, Romeu M, González S, Mallol J.Exp Dermatol. 2008 Aug;17(8):653-8. doi: 10.1111/j.1600-0625.2007.00684.x. Epub 2008 Feb 27.
  • 16. Less-known botanical cosmeceuticals.
    Baumann LS.Dermatol Ther. 2007 Sep-Oct;20(5):330-42. Review.
  • 17. Pharmacological immunomodulation of surgical trauma.
    Navarro-Zorraquino M, García-Alvarez F, Martínez-Fernández AR, Pastor C, Larrad L, Salinas JC, Lozano R.J Invest Surg. 2007 Sep-Oct;20(5):283-9.
  • 18. A Polypodium leucotomos extract inhibits solar-simulated radiation-induced TNF-alpha and iNOS expression, transcriptional activation, and apoptosis.
    Janczyk A, Garcia-Lopez MA, Fernandez-Peñas P, Alonso-Lebrero JL, Benedicto I, López-Cabrera M, Gonzalez S.Exp Dermatol. 2007 Oct;16(10):823-9.
  • 19. Polypodium leucotomos extract: a nutraceutical with photoprotective properties.
    Gonzalez S, Alonso-Lebrero JL, Del Rio R, Jaen P.Drugs Today (Barc). 2007 Jul;43(7):475-85. Review.
  • 20. Treatment of vitiligo vulgaris with narrow-band UVB and oral Polypodium leucotomos extract: a randomized double-blind placebo-controlled study.
    Middelkamp-Hup MA, Bos JD, Rius-Diaz F, Gonzalez S, Westerhof W.J Eur Acad Dermatol Venereol. 2007 Aug;21(7):942-50.



35% 40% Punicalagin Alpha+Beta HPLC

Botanical Source

Pericarpium Granati


25 kg/drum


Stored in cool & dry places, protected from direct sunlight and heat.


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