Best Herbal Extracts

Botanical Ingredient


Hesperidin is extracted from Citrus aurantium L. or Citrus sinensis Osbeck. Stanford Chemicals has been providing quality Hesperidin and many other natural plant extract for over 25 years.

SKU HE3004 Category

Hesperidin Safety Tips

Handling of Hesperidin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.


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  • 4. Molecular spectroscopic on interaction between Methyl hesperidin and Buman serum albumin.
    Li J, Wang S.Spectrochim Acta A Mol Biomol Spectrosc. 2012 Oct 23;102C:200-204. doi: 10.1016/j.saa.2012.10.012. [Epub ahead of print]
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  • 7. Kappa-opioid receptors mediate the antidepressant-like activity of hesperidin in the mouse forced swimming test.
    Filho CB, Fabbro LD, de Gomes MG, Goes AT, Souza LC, Boeira SP, Jesse CR.Eur J Pharmacol. 2012 Nov 20. doi:pii: S0014-2999(12)00934-X.  10.1016/j.ejphar.2012.11.003. [Epub ahead of print]
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    Xie RF, Zhou X, Shi ZN, Li YM, Li ZC.J Chromatogr Sci. 2012 Oct 31. [Epub ahead of print]
  • 11. Hesperidin prevents retinal and plasma abnormalities in streptozotocin-induced diabetic rats.
    Shi X, Liao S, Mi H, Guo C, Qi D, Li F, Zhang C, Yang Z.Molecules. 2012 Nov 1;17(11):12868-81. doi: 10.3390/molecules171112868.
  • 12. Hesperidinase encapsulation towards hesperitin production targeting improved bioavailability.
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  • 13. Hesperidin-3′-o-methylether is more potent than hesperidin in phosphodiesterase inhibition and suppression of ovalbumin-induced airway hyperresponsiveness.
    Yang YL, Hsu HT, Wang KH, Wang CS, Chen CM, Ko WC.Evid Based Complement Alternat Med. 2012;2012:908562. doi: 10.1155/2012/908562. Epub 2012 Oct 3.
  • 14. Synthesis and anti-hyperglycemic activity of hesperidin derivatives.
    Zhang B, Chen T, Chen Z, Wang M, Zheng D, Wu J, Jiang X, Li X.Bioorg Med Chem Lett. 2012 Dec 1;22(23):7194-7. doi: 10.1016/j.bmcl.2012.09.049. Epub 2012 Sep 23.
  • 15. Stability of bioactive polyphenols from honey during different extraction methods.
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  • 16. Evidence for the involvement of the serotonergic 5-HT(1A) receptors in the antidepressant-like effect caused by hesperidin in mice.
    Souza LC, de Gomes MG, Goes AT, Del Fabbro L, Filho CB, Boeira SP, Jesse CR.Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:103-9. doi: 10.1016/j.pnpbp.2012.09.003. Epub 2012 Sep 17.
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  • 18. Effect of natural cross-linkers incorporation in a self-etching primer on dentine bond strength.
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  • 19. Enzymatic bioconversion of citrus hesperidin by Aspergillus sojae naringinase: enhanced solubility of hesperetin-7-O-glucoside with in vitro inhibition of human intestinal maltase, HMG-CoA reductase, and growth of Helicobacter pylori.
    Lee YS, Huh JY, Nam SH, Moon SK, Lee SB.Food Chem. 2012 Dec 15;135(4):2253-9. doi: 10.1016/j.foodchem.2012.07.007. Epub 2012 Jul 14.
  • 20. Protective effects of sweet orange (Citrus sinensis) peel and their bioactive compounds on oxidative stress.
    Chen ZT, Chu HL, Chyau CC, Chu CC, Duh PD.Food Chem. 2012 Dec 15;135(4):2119-27. doi: 10.1016/j.foodchem.2012.07.041. Epub 2012 Jul 15.


Product Name




Molecular Formula


Molecular Weight


Botanical Source

Citrus aurantium L. or Citrus sinensis Osbeck


95% HPLC


Little yellow powder


25 kg/drum


Stored in cool & dry places, protected from direct sunlight and heat.

Shelf Life

2 years


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