Best Herbal Extracts

Botanical Ingredient

Hesperidin

Hesperidin is extracted from Citrus aurantium L. or Citrus sinensis Osbeck. Stanford Chemicals has been providing quality Hesperidin and many other natural plant extract for over 25 years.

SKU HE3004 Category

Hesperidin Safety Tips

Handling of Hesperidin should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

  • 1. Citrus flavonoids and lipid metabolism.
    Assini JM, Mulvihill EE, Huff MW.Curr Opin Lipidol. 2012 Dec 18. [Epub ahead of print]
  • 2. Radioprotective property of an aqueous extract from valeriana wallichii.
    Katoch O, Kaushik S, Kumar MS, Agrawala PK, Misra K.J Pharm Bioallied Sci. 2012 Oct;4(4):327-32. doi: 10.4103/0975-7406.103272.
  • 3. Food Ingredient Extracts of Cyclopia subternata (Honeybush): Variation in Phenolic Composition and Antioxidant Capacity.
    de Beer D, Schulze AE, Joubert E, de Villiers A, Malherbe CJ, Stander MA.Molecules. 2012 Dec 7;17(12):14602-24. doi: 10.3390/molecules171214602.
  • 4. Molecular spectroscopic on interaction between Methyl hesperidin and Buman serum albumin.
    Li J, Wang S.Spectrochim Acta A Mol Biomol Spectrosc. 2012 Oct 23;102C:200-204. doi: 10.1016/j.saa.2012.10.012. [Epub ahead of print]
  • 5. The inhibitory effect of polyphenols on human gut microbiota.
    Duda-Chodak A.J Physiol Pharmacol. 2012 Oct;63(5):497-503.
  • 6. Antioxidant activity and effective compounds of immature calamondin peel.
    Yu MW, Lou SN, Chiu EM, Ho CT.Food Chem. 2013 Feb 15;136(3-4):1130-5. doi: 10.1016/j.foodchem.2012.09.088. Epub 2012 Oct 2.
  • 7. Kappa-opioid receptors mediate the antidepressant-like activity of hesperidin in the mouse forced swimming test.
    Filho CB, Fabbro LD, de Gomes MG, Goes AT, Souza LC, Boeira SP, Jesse CR.Eur J Pharmacol. 2012 Nov 20. doi:pii: S0014-2999(12)00934-X.  10.1016/j.ejphar.2012.11.003. [Epub ahead of print]
  • 8. Major active components in grapefruit, orange, and apple juices responsible for OATP2B1-mediated drug interactions.
    Shirasaka Y, Shichiri M, Mori T, Nakanishi T, Tamai I.J Pharm Sci. 2013 Jan;102(1):280-8. doi: 10.1002/jps.23357. Epub 2012 Nov 6.
  • 9. Identification of flavonoids with trypsin inhibitory activity extracted from orange peel and green tea leaves.
    Shahwar D, Raza MA, Atta-Ur-Rahman.J Sci Food Agric. 2012 Sep 11. doi: 10.1002/jsfa.5910. [Epub ahead of print]
  • 10. Study on Spectrum-Effect Relationship of Rhizoma Rhei, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus and their Formula.
    Xie RF, Zhou X, Shi ZN, Li YM, Li ZC.J Chromatogr Sci. 2012 Oct 31. [Epub ahead of print]
  • 11. Hesperidin prevents retinal and plasma abnormalities in streptozotocin-induced diabetic rats.
    Shi X, Liao S, Mi H, Guo C, Qi D, Li F, Zhang C, Yang Z.Molecules. 2012 Nov 1;17(11):12868-81. doi: 10.3390/molecules171112868.
  • 12. Hesperidinase encapsulation towards hesperitin production targeting improved bioavailability.
    Furtado AF, Nunes MA, Ribeiro MH.J Mol Recognit. 2012 Nov;25(11):595-603. doi: 10.1002/jmr.2224.
  • 13. Hesperidin-3′-o-methylether is more potent than hesperidin in phosphodiesterase inhibition and suppression of ovalbumin-induced airway hyperresponsiveness.
    Yang YL, Hsu HT, Wang KH, Wang CS, Chen CM, Ko WC.Evid Based Complement Alternat Med. 2012;2012:908562. doi: 10.1155/2012/908562. Epub 2012 Oct 3.
  • 14. Synthesis and anti-hyperglycemic activity of hesperidin derivatives.
    Zhang B, Chen T, Chen Z, Wang M, Zheng D, Wu J, Jiang X, Li X.Bioorg Med Chem Lett. 2012 Dec 1;22(23):7194-7. doi: 10.1016/j.bmcl.2012.09.049. Epub 2012 Sep 23.
  • 15. Stability of bioactive polyphenols from honey during different extraction methods.
    Biesaga M, Pyrzynska K.Food Chem. 2013 Jan 1;136(1):46-54. doi: 10.1016/j.foodchem.2012.07.095. Epub 2012 Aug 1.
  • 16. Evidence for the involvement of the serotonergic 5-HT(1A) receptors in the antidepressant-like effect caused by hesperidin in mice.
    Souza LC, de Gomes MG, Goes AT, Del Fabbro L, Filho CB, Boeira SP, Jesse CR.Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:103-9. doi: 10.1016/j.pnpbp.2012.09.003. Epub 2012 Sep 17.
  • 17. [Study on in vitro and in vivo material base of Sini San by UPLC-PDA-MS/MS].
    Qiao Y, Wen J, Song Y, Lu X, Xiong Z, Li F.Zhongguo Zhong Yao Za Zhi. 2012 Jun;37(11):1672-6. Chinese.
  • 18. Effect of natural cross-linkers incorporation in a self-etching primer on dentine bond strength.
    Islam S, Hiraishi N, Nassar M, Yiu C, Otsuki M, Tagami J.J Dent. 2012 Dec;40(12):1052-9. doi: 10.1016/j.jdent.2012.08.015. Epub 2012 Sep 11.
  • 19. Enzymatic bioconversion of citrus hesperidin by Aspergillus sojae naringinase: enhanced solubility of hesperetin-7-O-glucoside with in vitro inhibition of human intestinal maltase, HMG-CoA reductase, and growth of Helicobacter pylori.
    Lee YS, Huh JY, Nam SH, Moon SK, Lee SB.Food Chem. 2012 Dec 15;135(4):2253-9. doi: 10.1016/j.foodchem.2012.07.007. Epub 2012 Jul 14.
  • 20. Protective effects of sweet orange (Citrus sinensis) peel and their bioactive compounds on oxidative stress.
    Chen ZT, Chu HL, Chyau CC, Chu CC, Duh PD.Food Chem. 2012 Dec 15;135(4):2119-27. doi: 10.1016/j.foodchem.2012.07.041. Epub 2012 Jul 15.

Details

Product Name

Hesperidin

CAS No.

520-26-3

Molecular Formula

C28H34O15

Molecular Weight

610.55

Botanical Source

Citrus aurantium L. or Citrus sinensis Osbeck

Purity

95% HPLC

Appearance

Little yellow powder

Package

25 kg/drum

Storage

Stored in cool & dry places, protected from direct sunlight and heat.

Shelf Life

2 years









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