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Home » Products » Botanical Ingredient » Berberine Hydrochloride

Berberine Hydrochloride

Chemical Structure of Berberine Hydrochloride

Berberine Hydrochloride is extracted from Berberis vulgaris. Stanford Chemicals has been providing quality Berberine Hydrochloride and many other natural plant extract for over 15 years.

Product Name

Berberine Hydrochloride

CAS No.

633-65-8

Molecular Formula

C20H18NO4

Molecular Weight

371.81

Botanical Source

Berberis vulgaris

Purity

97% HPLC

Appearance

Yellow hygroscopic powder

Package

25 kg/drum

Storage

Stored in cool & dry places, protected from direct sunlight and heat.

Shelf Life

2 years

Berberine Hydrochloride Safety Tips

Handling of Berberine Hydrochloride should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

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References
  • 1. Preparation and Evaluation of Orally Disintegrating Tablets Containing Taste-Masked Microcapsules of Berberine Hydrochloride.

    Hu X, Li Y, Zhang E, Wang X, Xing M, Wang Q, Lei J, Huang H.AAPS PharmSciTech. 2012 Nov 22. [Epub ahead of print]

  • 2. [Preparation and stuctural behavior of the inclusion complex of beta-cyclodextrin and coptisine hydrochloride].

    Chen HY, Jin Z, Chen SQ.Zhong Yao Cai. 2012 Jan;35(1):138-41. Chinese.

  • 3. [Study on compatibility extraction technology of Rhei Radix et Rhizoma, Scutellariae Radix and Phellodendri Chinensis Cortex].

    Zhou A, Yin H, Wang Z.Zhongguo Zhong Yao Za Zhi. 2012 Feb;37(4):461-5. Chinese.

  • 4. Using immobilized G-protein coupled receptors to screen bioactive traditional Chinese medicine compounds with multiple targets.

    Zhao X, Li Q, Bian L, Zheng X, Zheng J, Zhang Y, Li Z.J Pharm Biomed Anal. 2012 Nov;70:549-52. doi: 10.1016/j.jpba.2012.05.004. Epub 2012 May 15.

  • 5. Evaluation of a 13-hexyl-berberine hydrochloride topical gel formulation.

    Wei HL, Wang S, Xu F, Xu LF, Zheng JR, Chen Y.Drug Dev Ind Pharm. 2012 May 22. [Epub ahead of print]

  • 6. Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride.

    Zhu JX, Tang D, Feng L, Zheng ZG, Wang RS, Wu AG, Duan TT, He B, Zhu Q.Drug Dev Ind Pharm. 2012 May 8. [Epub ahead of print]

  • 7. Effect of berberine hydrochloride on grass carp Ctenopharyngodon idella serum bactericidal activity against Edwardsiella ictaluri.

    Ji C, Zhang de F, Li AH, Gong XN.Fish Shellfish Immunol. 2012 Jul;33(1):143-5. doi: 10.1016/j.fsi.2012.03.022. Epub 2012 Apr 12.

  • 8. [Extract berberine hydrochloride by aqueous two-phase system].

    Wen CF, Xiang XQ, Zeng WX, Wu T, Tian CL.Zhong Yao Cai. 2011 Oct;34(10):1608-11. Chinese.

  • 9. Berberine ameliorates COX-2 expression in rat small intestinal mucosa partially through PPARγ pathway during acute endotoxemia.

    Feng AW, Gao W, Zhou GR, Yu R, Li N, Huang XL, Li QR, Li JS.Int Immunopharmacol. 2012 Jan;12(1):182-8. doi: 10.1016/j.intimp.2011.11.009. Epub 2011 Dec 9.

  • 10. Berberine hydrochloride: anticancer activity and nanoparticulate delivery system.

    Tan W, Li Y, Chen M, Wang Y.Int J Nanomedicine. 2011;6:1773-7. doi: 10.2147/IJN.S22683. Epub 2011 Aug 24. Review.

  • 11. [Determination of ephedrine hydrochloride, pseudoephedrine hydrochloride and methylephedrine hydrochloride in maxingshigan decoction by CE].

    Yu LP, Wang XK, Luo JB.Zhong Yao Cai. 2011 Apr;34(4):620-3. Chinese.

  • 12. Tableting technology from the individual and new galenic alkaloid consisting preparations of the Phellodendron lavallei bark.

    Meskheli M, Vachnadze V, Kurdiani, Tsagareishvili N, Bakuridze A.Georgian Med News. 2011 Jun;(195):79-84.

  • 13. Enhancing effects of chitosan and chitosan hydrochloride on intestinal absorption of berberine in rats.

    Chen W, Fan D, Meng L, Miao Y, Yang S, Weng Y, He H, Tang X.Drug Dev Ind Pharm. 2012 Jan;38(1):104-10. doi: 10.3109/03639045.2011.592531. Epub 2011 Jul 20.

  • 14. Berberine regulated Gck, G6pc, Pck1 and Srebp-1c expression and activated AMP-activated protein kinase in primary rat hepatocytes.

    Ge Y, Zhang Y, Li R, Chen W, Li Y, Chen G.Int J Biol Sci. 2011;7(5):673-84. Epub 2011 May 24.

  • 15. Berberine hydrochloride attenuates cyclooxygenase-2 expression in rat small intestinal mucosa during acute endotoxemia.

    Feng AW, Yu C, Mao Q, Li N, Li QR, Li JS.Fitoterapia. 2011 Oct;82(7):976-82. doi: 10.1016/j.fitote.2011.05.013. Epub 2011 May 27.

  • 16. Identification of novel pregnane X receptor activators from traditional Chinese medicines.

    Yu C, Chai X, Yu L, Chen S, Zeng S.J Ethnopharmacol. 2011 Jun 14;136(1):137-43. doi: 10.1016/j.jep.2011.04.022. Epub 2011 Apr 16.

  • 17. [Changes of metabolic indices caused by berberin and extract, obtained from the bark of Phellodendron lavalei, introduced in subtropic regions of Georgia, in streptozotocin induced diabetic rats].

    Meskheli MB, Antelava NA, Bakuridze AD, Gongadze MV, Okudzhava MV.Georgian Med News. 2011 Feb;(191):61-8. Russian.

  • 18. [Antidiabetic activity of berberin and extract, obtained from the bark of Phellodendron lavalei, introduced in subtropic regions of Georgia, in streptozotocin induced diabetic rats].

    Meskheli MB, Antelava NA, Bakuridze AD, Berishvili ER, Pachkoriia KZ.Georgian Med News. 2011 Feb;(191):53-60. Russian.

  • 19. pH-sensitive and mucoadhesive microspheres for duodenum-specific drug delivery system.

    Liu YH, Zhu X, Zhou D, Jin Y, Zhao CY, Zhang ZR, Huang Y.Drug Dev Ind Pharm. 2011 Jul;37(7):868-74. doi: 10.3109/03639045.2010.546801. Epub 2011 Jan 14.

  • 20. Gateways to clinical trials.

    Tomillero A, Moral MA.Methods Find Exp Clin Pharmacol. 2010 Dec;32(10):749-73. doi: 10.1358/mf.2010.32.10.1573763.

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