Baical Skullcap Root Extract

Specification:

20%-95% Baicalin HPLC; 20%-95% Flavonoids UV

Botanical Source:

Baical Skullcap Root, Scutellaria Baicalensis Georgi (Lamiaceae)

Package:

25 kg/drum

Storage:

Stored in cool & dry places, protected from direct sunlight and heat.

Introduction:

Clearing heat and dampness, purging fire detoxification, bleeding. treatment for hot and humid, heat chest oue, hot and humid fullness, jaundice, hyperactivity cough, fever, polydipsia, hot spit blood bleed at the nose, sore boils, fetal irritability.

Baical Skullcap Root Extract Safety Tips

Handling of Baical Skullcap Root Extract should only be performed by personnel trained and familiar with handling of potent active pharmaceutical ingredients. Moderate to severe irritant to the skin and eyes.

References

1. Cytotoxic and antioxidant properties of selected Scutellaria species from the Western Ghats of Peninsular India.
Salini S, Chubicka T, Sasidharan N, Sindhu ER, Babu TD.Pharm Biol. 2012 Nov 5. [Epub ahead of print]
2. [Quadratic regression-orthogonal design optimization ethanol extraction craft of baicalin].
Shi L, Zhang ZW.Zhong Yao Cai. 2011 Dec;34(12):1946-50. Chinese.
3. Baicalin is anti-inflammatory in cigarette smoke-induced inflammatory models in vivo and in vitro: A possible role for HDAC2 activity.
Li L, Bao H, Wu J, Duan X, Liu B, Sun J, Gong W, Lv Y, Zhang H, Luo Q, Wu X, Dong J.Int Immunopharmacol. 2012 May;13(1):15-22. doi: 10.1016/j.intimp.2012.03.001. Epub 2012 Mar 13.
4. A simple isocratic HPLC method for the simultaneous determination of bioactive components of Scutellariae radix extract.
Islam MN, Chung HJ, Kim DH, Yoo HH.Nat Prod Res. 2012 Nov;26(21):1957-62. Epub 2012 Feb 3.
5. Gene expression profiling and pathway network analysis of hepatic metabolic enzymes targeted by baicalein.
Qin S, Chen J, Tanigawa S, Hou DX.J Ethnopharmacol. 2012 Mar 6;140(1):131-40. doi: 10.1016/j.jep.2011.12.046. Epub 2012 Jan 14.
6. Effect of baikal skullcap root (Scutellaria baicalensis radix) on cholesterol level and meat quality in rabbits fed a cholesterol rich diet.
Króliczewska B, Mi?ta D, Zawadzki W, Skiba T.Folia Biol (Krakow). 2011;59(3-4):169-73.
7. Detection of baicalin metabolites baicalein and oroxylin-a in mouse pancreas and pancreatic xenografts.
Lu QY, Zhang L, Moro A, Chen MC, Harris DM, Eibl G, Go VL.Pancreas. 2012 May;41(4):571-6. doi: 10.1097/MPA.0b013e318232e130.
8. Fast profiling of chemical constituents in Yiqing Capsule by ultra-performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry.
Zheng GD, Li K, Li YS, Liu EH.J Sep Sci. 2012 Jan;35(1):174-83. doi: 10.1002/jssc.201100736. Epub 2011 Nov 28.
9. Study of the chemical composition and antimicrobial activities of ethanolic extracts from roots of Scutellaria baicalensis Georgi.
Lu Y, Joerger R, Wu C.J Agric Food Chem. 2011 Oct 26;59(20):10934-42. doi: 10.1021/jf202741x. Epub 2011 Sep 30.
10. Extract of Scutellaria baicalensis Georgi root exerts protection against myocardial ischemia-reperfusion injury in rats.
Chan E, Liu XX, Guo DJ, Kwan YW, Leung GP, Lee SM, Chan SW.Am J Chin Med. 2011;39(4):693-704.
11. Effects of Scutellaria baicalensis on chronic cerebral hypoperfusion-induced memory impairments and chronic lipopolysaccharide infusion-induced memory impairments.
Hwang YK, Jinhua M, Choi BR, Cui CA, Jeon WK, Kim H, Kim HY, Han SH, Han JS.J Ethnopharmacol. 2011 Sep 1;137(1):681-9. doi: 10.1016/j.jep.2011.06.025. Epub 2011 Jun 21.
12. Neuroprotective effect of oral S/B remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) on iron-induced neurodegeneration in the nigrostriatal dopaminergic system of rat brain.
Lin AM, Ping YH, Chang GF, Wang JY, Chiu JH, Kuo CD, Chi CW.J Ethnopharmacol. 2011 Apr 12;134(3):884-91. doi: 10.1016/j.jep.2011.01.056. Epub 2011 Feb 4.
13. Flavones from root of Scutellaria baicalensis Georgi: drugs of the future in neurodegeneration?
Gasiorowski K, Lamer-Zarawska E, Leszek J, Parvathaneni K, Yendluri BB, B?ach-Olszewska Z, Aliev G.CNS Neurol Disord Drug Targets. 2011 Mar;10(2):184-91. Review.
14. Flavonoid pharmacokinetics and tissue distribution after repeated dosing of the roots of Scutellaria baicalensis in rats.
Hou YC, Lin SP, Tsai SY, Ko MH, Chang YC, Chao PD.Planta Med. 2011 Mar;77(5):455-60. doi: 10.1055/s-0030-1250433. Epub 2010 Oct 18.
15. Baicalin increases VEGF expression and angiogenesis by activating the ERR{alpha}/PGC-1{alpha} pathway.
Zhang K, Lu J, Mori T, Smith-Powell L, Synold TW, Chen S, Wen W.Cardiovasc Res. 2011 Feb 1;89(2):426-35. doi: 10.1093/cvr/cvq296. Epub 2010 Sep 16.
16. Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer.
Chan E, Wong CY, Wan CW, Kwok CY, Wu JH, Ng KM, So CH, Au AL, Poon CC, Seto SW, Kwan YW, Yu PH, Chan SW.Am J Chin Med. 2010;38(4):815-27.
17. Baicalin attenuates inflammation by inhibiting NF-kappaB activation in cigarette smoke induced inflammatory models.
Lixuan Z, Jingcheng D, Wenqin Y, Jianhua H, Baojun L, Xiaotao F.Pulm Pharmacol Ther. 2010 Oct;23(5):411-9. doi: 10.1016/j.pupt.2010.05.004. Epub 2010 May 23.
18. Secondary metabolite mapping identifies Scutellaria inhibitors of human lung cancer cells.
Gao J, Zhao H, Hylands PJ, Corcoran O.J Pharm Biomed Anal. 2010 Nov 2;53(3):723-8. doi: 10.1016/j.jpba.2010.04.019. Epub 2010 Apr 20.
19. The effect of Scutellaria baicalensis on the signaling network in hepatocellular carcinoma cells.
Ye F, Che Y, McMillen E, Gorski J, Brodman D, Saw D, Jiang B, Zhang DY.Nutr Cancer. 2009;61(4):530-7. doi: 10.1080/01635580902803719.
20. Anti-inflammatory effects of Scutellaria baicalensis water extract on LPS-activated RAW 264.7 macrophages.
Yoon SB, Lee YJ, Park SK, Kim HC, Bae H, Kim HM, Ko SG, Choi HY, Oh MS, Park W.J Ethnopharmacol. 2009 Sep 7;125(2):286-90. doi: 10.1016/j.jep.2009.06.027. Epub 2009 Jul 3.

Reference Substances

Botanical Ingredient

Standard Herbal Extract