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Curculigoside is a phenolic glycoside from Curculigo orchioides with antioxidant, anti-inflammatory, neuroprotective, and osteoprotective properties, explored for therapeutic potential in neurodegenerative diseases, inflammatory disorders, and bone health enhancement.

SKU HE5247 Category


Curculigoside’s ability to interact with and modulate various biological targets underpins its therapeutic potential for treating a wide range of conditions, including neurodegenerative diseases, inflammatory disorders, and bone degenerative diseases.

Curculigoside Key Features

– Natural Source: Extracted from Curculigo orchioides Gaertn, known for its traditional use in Ayurvedic and Chinese medicine.

– Bioactivities: Demonstrates antioxidant, anti-inflammatory, neuroprotective, and osteoprotective effects.

– Mechanism of Action: Works by scavenging free radicals, inhibiting pro-inflammatory cytokines, and modulating signaling pathways involved in neuroprotection and bone health.

Curculigoside Applications

– Neuroprotective Treatments: Its neuroprotective properties make curculigoside a candidate for research into treatments for neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease.

– Anti-inflammatory Therapy: Potential applications in managing chronic inflammatory conditions, benefiting conditions like arthritis and other inflammatory diseases.

– Bone Health: The osteoprotective activity of curculigoside suggests its usefulness in treating or preventing osteoporosis and promoting bone healing.

Curculigoside Functions

– Reduction of Oxidative Stress: Curculigoside acts as an antioxidant, neutralizing free radicals and reducing oxidative damage to cells.

– Inhibition of Inflammatory Pathways: Modulates the production of inflammatory mediators, helping to reduce inflammation and its related damage in tissues.

– Protection of Neuronal Cells: Offers protection against neuronal injury and degeneration, supporting nerve health and function.

– Promotion of Bone Formation: Encourages bone formation and protects against bone loss, indicating potential benefits for bone health and recovery.



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